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Bin-Kuan Chou
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Eicosanoids
G-CSF
Mobilization
Transplantation
Full List of Publications Via Pubmed
Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation.
Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell - Cell. 2018 Jan 11
Gene Therapy for "Bubble Boy" Disease - Cell. 2016 Jul 14
Differential stem- and progenitor-cell trafficking by prostaglandin E2. - Nature. 2013 Mar 21;495(7441):365-9
Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis. - Nat Med. 2012 Dec;18(12):1786-96
Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells.
Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators - Cell Stem Cell. 2016 Oct 6
Role of lipegfilgrastim in the management of chemotherapy-induced neutropenia. - Int J Nanomedicine. 2015 Apr 1, 10: 2647-52
Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1. - Leukemia 2015 Feb;29(2):433-40
Bleeding the Laboratory Mouse: Not All Methods are Equal - Exp. Hematology, 2015, Epub ahead of print
Hematopoietic Stem and Progenitor Cell Mobilization In Mice. - Methods Mol Biol. 2014;1185:43-64
New G-CSF agonists for neutropenia therapy. - Expert Opin Investig Drugs. 2014 Jan, 23(1):21-35
Pharmacologic increase in HIF1A enhances hematopoietic stem, progenitor homing & engraftment. - Blood. 2014 Jan 9; 123(2):203-7
Concise review: Sowing the seeds of a fruitful harvest: hematopoietic stem cell mobilization. - Stem Cells. 2013 Dec, 31 (12):2599-606
Prostaglandin E2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness. - Blood 2013 Oct 24; 122(17):2997-3000
Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation. - Blood. 2013 Oct 24;122(17):3074-81
SIMPL enhancement of tumor necrosis factor-A dependent p65-MED1 complex formation is required for mammalian hematopoietic stem and progenitor cell function. - PLoS One. 2013 Apr 22;8(4):e61123
Recovery from hematopoietic injury by modulating prostaglandin E(2) signaling post-irradiation. - Blood Cells Mol Dis. 2013 Mar;50(3):147-53
The stem cell niche: tissue physiology at a single cell level - J Clin Invest. 2012 Sep;122(9):3029-34
Expansion of bone marrow neutrophils following G-CSF administration in mice results in osteolineage cell apoptosis and mobilization of hematopoietic stem and progenitor cells - Leukemia. 2012 Nov;26(11):2375-83
Hematopoietic stem cell mobilization with agents other than G-CSF - Methods Mol Biol. 2012;904:49-67
Blockade of prostaglandin E2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells - Blood. 2012 Feb 16;119(7):1671-82
Pleiotropic effects of prostaglandin E2 in hematopoiesis; prostaglandin E2 and other eicosanoids regulate hematopoietic stem and progenitor cell function. - Prostaglandins Other Lipid Mediat. 2011 Nov;96(1-4):3-9
Many mechanisms mediating mobilization: an alliterative review. - Curr Opin Hematol. 2011 Jul;18(4):231-8
How beneficial is the use of NSAIDs in stem-cell transplantation? - Epert Opin Hematol. 2011 Jul; 18 (4):231-8
Pulse exposure of haematopoietic grafts to prostaglandin E2 in vitro facilitates engraftment and recovery - Cell Prolif. 2011 Apr;44 Suppl 1:22-9
Mobilization of hematopoietic stem cells from the bone marrow niche to the blood compartment - Stem Cell Res Ther. 2011 Mar 14;2(2):13
Eicosanoid regulation of hematopoiesis and hematopoietic stem and progenitor trafficking - Leukemia. 2010 Dec;24(12):1993-2002
A spoonful of sugar helps the medicine go down: a novel technique to improve oral gavage in mice. - J Am Assoc Lab Anim Sci. 2010 May;49(3):329-34
Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation - Blood. 2009 May 28;113(22):5444-55
